- are known, 2-
imidazolines, 3-
imidazolines, and 4-
imidazolines. The 2- and 3-
imidazolines contain an
imine center,
whereas the 4-
imidazolines contain an...
-
Imidazoline receptors are the
primary receptors on
which clonidine and
other imidazolines act.
There are
three main
classes of
imidazoline receptor: I1...
- 2-
Imidazoline (Preferred
IUPAC name: 4,5-dihydro-1H-imidazole) is one of
three isomers of the nitrogen-containing
heterocycle imidazoline, with the formula...
-
example of autoreceptor. However, it is now
known that
clonidine binds to
imidazoline receptors with a much
greater affinity than α2 receptors,
which would...
-
Selected examples are:
Brimonidine Clonidine (mixed alpha2-adrenergic and
imidazoline-I1
receptor agonist)
Dexmedetomidine Fadolmidine Guanfacine, (preference...
-
peripheral vasomotor structures.
Rilmenidine is a
imidazoline analog and
shows greater selectivity for
imidazoline receptors than for
cerebral alpha2-adrenergic...
- the
presence of para-toluenesulfonic acid to form the
corresponding imidazoline, this
being xylometazoline.
Carbon disulfide can also be used as a catalyst...
-
certain oral
medications (e.g.,
sympathomimetic amines and
various 2-
imidazolines) that
constrict blood vessels in the
lining of the nose,
although evidence...
- α2-adrenergic receptors, with the
sigma σ1 and σ2 receptors, and with the
imidazoline I1 receptor. It is
thought that
agonism of the
serotonin 5-HT2A receptor...
-
vascular resistance.: 201–203
Clonidine also acts as an
agonist at
imidazoline-1 (I1)
receptors in the brain, and it is
hypothesized that this effect...
