- l-
Iduronic acid (IUPAC abbr.: IdoA) is the
major uronic acid
component of the
glycosaminoglycans (GAGs)
dermatan sulfate, and heparin. It is also present...
-
Naturally occurring uronic acids are d-glucuronic acid, d-galacturonic acid, l-
iduronic acid and d-mannuronic acid. Mohnen, D. (2008). "Pectin
structure and biosynthesis"...
- GlcUA(2S) = 2-O-sulfo-β-D-glucuronic acid
IdoUA = α-L-
iduronic acid IdoUA(2S) = 2-O-sulfo-α-L-
iduronic acid Gal = β-D-galactose Gal(6S) = 6-O-sulfo-β-D-galactose...
- IdoA-GlcNS GlcA = β-D-glucuronic acid, IdoA = α-L-
iduronic acid, IdoA(2S) = 2-O-sulfo-α-L-
iduronic acid,
GlcNAc = 2-deoxy-2-acetamido-α-D-glucopyranosyl...
- of
disaccharide units that contain, N-acetyl
galactosamine (GalNAc) and
iduronic acid (IdoA).
These repeating units are
sulfated at a
variety of positions...
- the
human body are
excreted in the
urine as
their glucuronate salts, and
iduronic acid is a
component of some
structural complexes such as proteoglycans...
- example, D-mannuronic (C-2), D-alluronic (C-3), D-galacturonic (C-4), and L-
iduronic acid (C-5) are
epimers of
glucuronic acid. The
nonplanar pyranose rings...
- is
responsible for
breaking down a
molecule called unsulfated alpha-L-
iduronic acid. This is a
uronic acid
found in the GAGs
dermatan sulfate and heparan...
- naturally-occurring
polysaccharide of O-sulfated N-acetyl-D-galatosamine, L-
iduronic acid, and D-glucuronic acid that has been
clinically used as an antithrombotic...
- thus an aldose.
Idose is not
found in nature, but its
oxidized derivative iduronic acid, is a
component of
dermatan sulfate and
heparan sulfate,
which are...
