- also
known as
IGFBP-3, is a
protein that in
humans is
encoded by the IGFBP3 gene.
IGFBP-3 is one of six IGF
binding proteins (
IGFBP-1 to
IGFBP-6) that have...
- The insulin-like
growth factor-binding
protein (
IGFBP)
serves as a
transport protein for insulin-like
growth factor 1 (IGF-1).
Approximately 98% of IGF-1...
-
hormone (GH). Most of IGF-1 is
bound to one of 6
binding proteins (IGF-BP).
IGFBP-1 is
regulated by insulin. IGF-1 is
produced throughout life; the highest...
- high-affinity IGF-binding
proteins (IGFBP1 to IGFBP7), as well as ****ociated
IGFBP degrading enzymes,
referred to
collectively as proteases. The IGF "axis"...
- the liver. IGF-1 has six
binding proteins (
IGFBPs),
exhibiting different effects on body tissues,
where IGFBP-3 is most
abundant in
human circulation. IGF-1...
-
binding to its receptors. IGFBP7
binds to IGF with low
affinity compared to
IGFBPs 1-6. It also
stimulates cell adhesion. The
protein is
implicated in some...
-
clinical evaluation may
include laboratory analysis of
basal GH, IGF-1 and
IGFBP levels, GH
stimulation testing, and/or GH
trial therapy.
People with LS...
- Met135-Lys bond in insulin-like
growth factor binding protein (
IGFBP)-4, and the Ser143-Lys bond in
IGFBP-5 This
enzyme belongs to the
peptidase family M43. Pappalysin-1...
-
Mecasermin rinfabate (INN, USAN) (brand name Iplex), also
known as rhIGF-1/rh
IGFBP-3, is a drug
consisting of
recombinant human insulin-like
growth factor...
- (IGF)-I and
estrogen administration on IGF-I, IGF
binding protein (
IGFBP)-2, and
IGFBP-3 in
anorexia nervosa: a randomized-controlled study". J. Clin. Endocrinol...
