Definition of Hypermutation. Meaning of Hypermutation. Synonyms of Hypermutation

- Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g. microbes)...
- experimental results in the fields of epigenetics, genetics, and somatic hypermutation demonstrated the possibility of transgenerational epigenetic inheritance...
- Reed–Sternberg cells have undergone both V(D)J recombination and somatic hypermutation, establishing an origin from a germinal center or postgerminal center...
- undergo a high rate of point mutation, by a process called somatic hypermutation (SHM). SHM results in approximately one nucleotide change per variable...
- immunoglobulin of germinal center B cells and as a direct result of somatic hypermutation (SHM) and selection by TFH cells. The process is thought to involve...
- (AID) that is essential for class switch recombination and somatic hypermutation. He was elected as a foreign ****ociate of the National Academy of Sciences...
- promotes B cell proliferation, immunoglobulin class switching, and somatic hypermutation as well as sustains T cell growth and differentiation. T cell-derived...
- specialised structures called germinal centers. This process involves somatic hypermutation, resulting in genetic changes that enhance the antibody's affinity....
- outside the lymphoid system. A major step in affinity maturation, somatic hypermutation helps B cells produce antibodies with greater antigen affinity. Somatic...
- proliferate, differentiate, and mutate their antibody genes (through somatic hypermutation aimed at achieving higher affinity) during a normal immune response;...