Definition of Hypermutation. Meaning of Hypermutation. Synonyms of Hypermutation

Here you will find one or more explanations in English for the word Hypermutation. Also in the bottom left of the page several parts of wikipedia pages related to the word Hypermutation and, of course, Hypermutation synonyms and on the right images related to the word Hypermutation.

Definition of Hypermutation

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Meaning of Hypermutation from wikipedia

- Somatic hypermutation (or SHM) is a cellular mechanism by which the immune system adapts to the new foreign elements that confront it (e.g. microbes)...
- (AID) that is essential for class switch recombination and somatic hypermutation. He was elected as a foreign ****ociate of the National Academy of Sciences...
- experimental results in the fields of epigenetics, genetics, and somatic hypermutation demonstrated the possibility of transgenerational epigenetic inheritance...
- undergo a high rate of point mutation, by a process called somatic hypermutation (SHM). SHM results in approximately one nucleotide change per variable...
- outside the lymphoid system. A major step in affinity maturation, somatic hypermutation helps B cells produce antibodies with greater antigen affinity. Somatic...
- proliferate, differentiate, and mutate their antibody genes (through somatic hypermutation aimed at achieving higher affinity) during a normal immune response;...
- Reed–Sternberg cells have undergone both V(D)J recombination and somatic hypermutation, establishing an origin from a germinal center or postgerminal center...
- promotes B cell proliferation, immunoglobulin class switching, and somatic hypermutation as well as sustains T cell growth and differentiation. T cell-derived...
- class switch from IgM/IgD to other antibody isotypes and drives somatic hypermutation during clonal proliferation. The switched antibodies acquire better...
- specialised structures called germinal centers. This process involves somatic hypermutation, resulting in genetic changes that enhance the antibody's affinity....