- Methylation, in the
chemical sciences, is the
addition of a
methyl group on a substrate, or the
substitution of an atom (or group) by a
methyl group. Methylation...
-
genes had
hypermethylated promoters in
nearly 100% of
colon cancers. They also
indicated 11
microRNAs whose promoters were
hypermethylated in
colon cancers...
- same set of
hypermethylated CpG
islands as in a glioma, and this
clinical distinctness of
tumors can be
interpreted by doctors.
Hypermethylated CpG islands...
- miR-155,
which down-regulates MLH1. Twenty-two DNA
repair genes with
hypermethylated promoters, and
reduced or
absent expression, were
found to
occur among...
-
colorectal cancers. Of the
hypermethylated genes, 10 were
hypermethylated in 100% of
colon cancers, and many
others were
hypermethylated in more than 50% of...
-
region of the
mouse brain there are 675
demethylated genes and 613
hypermethylated genes. However,
memories do not
remain in the hippocampus, but after...
- cancer.
These included 147
hypermethylated and 27
hypomethylated genes. Of the
hypermethylated genes, 10 were
hypermethylated in 100% of
colon cancers and...
- have
hypermethylated promoters (repressing gene expression) in more than 20% of
liver cancers, with
seven of
these genes being hypermethylated in more...
- were
evaluated in non-small cell lung
cancer (NSCLC) tumors, 42% were
hypermethylated in the NEIL1
promoter region. This was the most
frequent DNA repair...
-
island in
their promoter region. In
colon cancers, in
addition to
hypermethylated genes,
several hundred other genes have
hypomethylated (under-methylated)...
