-
Serine hydroxymethyltransferase (SHMT) is a
pyridoxal phosphate (PLP) (Vitamin B6)
dependent enzyme (EC 2.1.2.1)
which plays an
important role in cellular...
- In biochemistry, a
transferase is any one of a
class of
enzymes that
catalyse the
transfer of
specific functional groups (e.g. a
methyl or
glycosyl group)...
- In enzymology, a 3-methyl-2-oxobutanoate
hydroxymethyltransferase (EC 2.1.2.11) is an
enzyme that
catalyzes the
chemical reaction 5,10-methylenetetrahydrofolate...
- of
tetrahydrofolate with serine,
catalyzed by the
enzyme serine hydroxymethyltransferase.
Methylenetetrahydrofolate is a
source of the
equivalent of formaldehyde...
- In enzymology, a
deoxycytidylate 5-
hydroxymethyltransferase (EC 2.1.2.8) is an
enzyme that
catalyzes the
chemical reaction 5,10-methylenetetrahydrofolate...
- (EC 1.1.1.95), serC (EC 2.6.1.52), and serB (EC 3.1.3.3).
Serine hydroxymethyltransferase (SMHT) also
catalyzes the
biosynthesis of
glycine (retro-aldol...
- In enzymology, a D-alanine 2-
hydroxymethyltransferase (EC 2.1.2.7) is an
enzyme that
catalyzes the
chemical reaction 5,10-methylenetetrahydrofolate + D-alanine...
-
Serine hydroxymethyltransferase 2 is an
enzyme that in
humans is
encoded by the SHMT2 gene. GRCh38:
Ensembl release 89: ENSG00000182199 – Ensembl, May...
- must also be
tightly controlled to
avoid self-poisoning.
Serine hydroxymethyltransferase can
decompose serine into
formaldehyde and glycine,
according to...
- from 3-phosphoglycerate. In most organisms, the
enzyme serine hydroxymethyltransferase catalyses this
transformation via the
cofactor pyridoxal phosphate:...
