-
groups include hydroxamates, carboxylates, thiols, and phosphinyls.
Hydroxymates are
particularly potent inhibitors of MMPs and
other zinc-dependent enzymes...
- (2000)
Bexarotene (Targretin) a
retinoid (2006)
Vorinostat (Zolinza) a
hydroxymate histone deacetylase (HDAC)
inhibitor (2009)
Romidepsin (Istodax) a cyclic...
- synthetic.
Several potent MMP
inhibitors have been identified,
including hydroxymates, thiols, carbamoylphosphonates, hydroxyureas, hydrazines, β-lactams,...
