- 2e− + 2H+ → R3C−OH + H2O
Since O2
itself is a slow and
unselective hydroxylating agent,
catalysts are
required to
accelerate the pace of the process...
- 4-cresol:acceptor
oxidoreductase (methyl-
hydroxylating).
Other names in
common use
include p-cresol–(acceptor)
oxidoreductase (
hydroxylating), and p-cresol methylhydroxylase...
-
enzymatically active domains with
catalytic activities -
peptidylglycine alpha-
hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating...
- the form of metabolites, with only 2%
remaining unchanged.
Conjugated hydroxylated derivatives of
ketamine (80%)
followed by
dehydronorketamine (16%) are...
- S2CID 27787938. Methamphetamine, a
central nervous system stimulant drug, is p-
hydroxylated by CYP2D6 to less
active p-OH-methamphetamine. "Adderall XR Prescribing...
- Aromatic-ring-
hydroxylating dioxygenases (ARHD)
incorporate two
atoms of
dioxygen (O2) into
their substrates in the
dihydroxylation reaction. The product...
-
serum DβH
activity was
studied in two ways. First, in vivo
ability to β-
hydroxylate the
synthetic substrate hydroxyamphetamine was
compared in two subjects...
- NADPH2:oxygen
oxidoreductase (20-
hydroxylating, ester-producing), 17alpha-hydroxyprogesterone, NADPH2:oxygen
oxidoreductase (20-
hydroxylating, side-chain cleaving)...
-
incorporating the
small exon 13A. LH1 and LH3
hydroxylate lysyl residues in the
collagen triple helix,
whereas LH2b
hydroxylates lysyl residues in the telopeptides...
-
preventing the
oxygen from
escaping as
toxic hydrogen peroxide. 4-HPA is then
hydroxylated via a
dienone intermediate and
released as 3,4-DHPA; with the peroxide...
