-
forms is
called a
hydroxamate.
Deprotonation occurs at the −N(−OH)− group, with the
hydrogen atom
being removed,
resulting in a
hydroxamate anion R−C(=O)−N(−O−)−R'...
-
major groups of siderop****s
include the
catecholates (phenolates),
hydroxamates and
carboxylates (e.g.
derivatives of
citric acid).
Citric acid can also...
-
contain a
hydroxamate (-CONHOH)
group that
binds the zinc atom in the
active site of the MMP enzyme,
therefore this
group is
called "
hydroxamate-based MMP...
- The
Lossen rearrangement is the
conversion of a
hydroxamate ester to an isocyanate.
Typically O-acyl, sulfonyl, or
phosphoryl O-derivative are emplo****...
-
transporter BtuB, Fe(III)-pyochelin
receptor FptA,
receptor FepA,
ferric hydroxamate uptake receptor FhuA,
transporter FecA, and
pyoverdine receptor FpvA...
-
Vanhaecke T,
Papeleu P,
Elaut G,
Rogiers V (June 2004). "Trichostatin A-like
hydroxamate histone deacetylase inhibitors as
therapeutic agents:
toxicological point...
-
modified ornithine residues with
hydroxamate groups [-N(OH)C(=O)C-]. The 6
oxygen atoms from the
three hydroxamate groups bind Fe(III) in near perfect...
- post-exposure, to
inhibition by
protease inhibitors, e.g., zinc-coordinating
hydroxamates. University-based
ophthalmologists in the US and
Canada further refined...
-
Rhodotorulic acid is the
smallest of the 2,5-****topiperazine
family of
hydroxamate siderop****s
which are high-affinity
chelating agents for
ferric iron...
- (January 2021). "Lead
optimization of 2-hydroxymethyl
imidazoles as non-
hydroxamate LpxC inhibitors:
Discovery of TP0586532".
Bioorganic &
Medicinal Chemistry...
