- In chemistry,
dimerization is the
process of
joining two
identical or
similar molecular entities by bonds. The
resulting bonds can be
either strong or...
- In biochemistry, a
protein dimer is a
macromolecular complex or
multimer formed by two
protein monomers, or
single proteins,
which are
usually non-covalently...
-
homodimers formed either by cross-display or by a disulfide-linked
homodimerization mechanism, it is
proposed that such HMW
aggregates survive on the cell...
-
activation results from
heterodimerization with
another ERBB
member or by
homodimerization when HER2
concentration are high, for
instance in cancer. Amplification...
- AP20187 is a
ligand that can
induce homodimerization of
fusion proteins containing the F36V
mutant of an FKBP domain(FKBPF36V),
available commercially...
- STAT3,
which is
additionally phosphorylated by JAK1 and TYK2. STAT3
homodimerizes,
moves to the
cellular nucleus, and
activates gene transcription. The...
-
Pirenzepine has been
investigated for use in
myopia control. It
promotes the
homodimerization or
oligomerisation of M1 receptors. AFDX-384
Telenzepine Stolerman...
- also
known as Nrf1, Nrf-1, NRF1 and NRF-1,
encodes a
protein that
homodimerizes and
functions as a
transcription factor which activates the expression...
-
activation of
several cellular processes. When HGF
binds c-MET, the
receptor homodimerizes and self-phosphorylates to form an SH2
recognition domain. The downstream...
-
transcriptional complex necessary for a
productive T-cell response. Instead, NFAT
homodimerizes,
functioning as a
transcriptional factor that
induces anergy in the...
