Definition of Homocitrate. Meaning of Homocitrate. Synonyms of Homocitrate

- certain nitrogenase proteins. Biochemists often refer to this cofactor as homocitrate, which is the conjugate bases that predominate in neutral aqueous solutions...
- In enzymology, a homocitrate synthase (EC 2.3.3.14) is an enzyme that catalyzes the chemical reaction acetyl-CoA + H2O + 2-oxoglutarate ⇌ {\displaystyle...
- by homocitrate-synthase (HCS) (E.C 2.3.3.14) to give the intermediate homocitryl‑CoA, which is hydrolysed by the same enzyme to produce homocitrate. Homocitrate...
- imidazole group of a histidine residue. Also bound to Mo is a bidentate homocitrate cofactor, leading to octahedral geometry. Crystallographic analysis of...
- acetyl-CoA with α-ketoglutarate, which gives homocitrate. This reaction is catalyzed by homocitrate synthase. Homocitrate is then converted to homoaconitate by...
- the by-product l-lysine inhibiting the enzyme homocitrate synthase. α-ketoglutarate + AcCoA → homocitrate → L-α-aminoadipic acid → L-lysine + β-lactam...
- AH, Cook PF (September 2004). "Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae". Biochemistry. 43 (37): 11790–11795...
- Nitrogenase include two P-clusters ([8Fe-7S]) and two FeMocos ([7Fe-9S-C-Mo-R homocitrate]). Carbon monoxide dehydrogenase and acetyl coenzyme-A synthase each...
- nitrogen fixation in the absence of a nitrogen source in the medium. Homocitrate ions play a certain role in the processes of nitrogen fixation by Azotobacter...
- α-aminoadipate pathway for lysine biosynthesis, where it is made from homocitrate by homoaconitase. It is converted to homoisocitrate by homoisocitrate...