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Hexosaminidase (EC 3.2.1.52, β-acetylaminodeoxyhexosidase, N-acetyl-β-D-
hexosaminidase, N-acetyl-β-
hexosaminidase, N-acetyl
hexosaminidase, β-hexosaminidase...
- gene on
chromosome 15,
which codes a
subunit of the
hexosaminidase enzyme known as
hexosaminidase A. It is
inherited in an
autosomal recessive manner...
-
disorder caused by the
inherited deficiency to
create functional beta-
hexosaminidases A and B.
These catabolic enzymes are
needed to
degrade the neuronal...
-
Hexosaminidase A (alpha polypeptide), also
known as HEXA, is an
enzyme that in
humans is
encoded by the HEXA gene,
located on the 15th chromosome. Hexosaminidase...
- Beta-
hexosaminidase subunit beta is an
enzyme that in
humans is
encoded by the HEXB gene.
Hexosaminidase B is the beta
subunit of the
lysosomal enzyme...
-
genetic disorders that
result from a
deficiency of the
enzyme beta-
hexosaminidase. This
enzyme catalyzes the
biodegradation of
fatty acid derivatives...
- In 2011,
researchers discovered that
pyrimethamine can
increase β-
hexosaminidase activity, thus
potentially slowing down the
progression of late-onset...
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Infantile Juvenile Adult onset Tay–Sachs
Juvenile hexosaminidase A
deficiency Chronic hexosaminidase A
deficiency Glucocerebroside Gaucher disease Type...
-
substrate 4-nitrophenyl N-acetyl-β-D-glucosamine.
Dispersin B is a β-
hexosaminidase that
specifically hydrolyzes β-1,6-glycosidic
linkages of acetylglucosamine...
- are 3
forms of beta-
hexosaminidase:
hexosaminidase A is a trimer, with one alpha, one beta-A and one beta-B chain;
hexosaminidase B is a
tetramer of two...
