- a
PROTAC works by
inducing selective intracellular proteolysis. A
heterobifunctional molecule with two
active domains and a linker,
PROTACs consist of...
- sophisticated,
there has been an
increase in need for
heterobifunctional PEGs for conjugation.
These heterobifunctional PEGs are very
useful in
linking two entities...
- as an
activated N-hydroxysuccinimide ester, are
called maleimide heterobifunctional reagents . One
natural maleimide is the
cytotoxic showdomycin from...
-
contributions to the
field of
induced proximity through his work in
creating heterobifunctional molecules that "hijack"
cellular processes by
inducing the interaction...
- ROS,
thioketals can be
selectively cleaved. ROS
successfully cleave heterobifunctional thioketal linkers,
which have been
found to have
therapeutic potential...
-
Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC) is a
heterobifunctional amine-to-sulfhydryl crosslinker,
which contains two
reactive groups...
-
collaboration with
Craig Crews (Yale),
conceived the idea of
using heterobifunctional small molecules,
referred to as PROTACs, to
tether cellular proteins...
- efficiency. The
modular structure of TMP-HaloTag
makes it an
ideal heterobifunctional tool for use in
chemically induced dimerization (CID). Additionally...
-
succinimidyl trans-4-(maleimidylmethyl)cyclohexane-1-carboxylate, is a
heterobifunctional crosslinker, a type of
chemical reagent that
contains two reactive...
-
Company Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate -
heterobifunctional chemical linker This
disambiguation page
lists articles ****ociated...
