- The
concept of
haptens emerged from the work of
Austrian immunologist Karl Landsteiner, who also
pioneered the use of
synthetic haptens to
study immunochemical...
-
hapten.
Haptens are low-molecular-weight
compounds that may be
bound by antibodies, but
cannot elicit an
immune response. Consequently, the
haptens themselves...
-
lysine residues for
coupling haptens allows a high
hapten:carrier
protein ratio,
increasing the
likelihood of
generating hapten-specific antibodies. In addition...
- [3.2.1] octane-2-carboxamido-hexanoic acid
Cocaine haptens that
create catalytic anti-bodies
require transitional states as affected...
-
while T cell
reaction to
haptens persisted. The
presentation of
peptides by HLA on APC
takes > 4hr
pulsing (uptake of
hapten modified protein, processing...
- PFP
esters are
useful for
attaching fluorop****s such as
fluorescein or
haptens to
primary amines in biomolecules. They also are
valuable in laboratory...
-
radiolabeled monovalent and
divalent haptens with dual
specificity monoclonal antibody conjugates:
enhanced divalent hapten affinity for cell-bound antibody...
-
diphtheria toxin,
currently used as a
carrier protein for
polysaccharides and
haptens to make them immunogenic.
There is some
dispute about the
toxicity of CRM197...
-
because of the
small size of
metal ions may
prevent them from
becoming haptens.
Poisoning from
metallosis is rare, but
cobaltism is an
established health...
-
different individuals,
combine with epithelial-derived proteins,
forming haptens which bind with
Langerhans cells in the mucosa,
which in turn
present the...
