Definition of HMGCR. Meaning of HMGCR. Synonyms of HMGCR

Here you will find one or more explanations in English for the word HMGCR. Also in the bottom left of the page several parts of wikipedia pages related to the word HMGCR and, of course, HMGCR synonyms and on the right images related to the word HMGCR.

Definition of HMGCR

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Meaning of HMGCR from wikipedia

- reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-controlling enzyme (NADH-dependent, EC 1.1.1.88; NADPH-dependent...
- Morales-Rosado JA, Schwab TL, et al. (2023-06-01). "Bi-allelic variants in HMGCR cause an autosomal-recessive progressive limb-girdle muscular dystrophy"...
- Statin-****ociated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people...
- autoimmune disease. Some specific examples of autoantibodies are Anti-Jo-1, Anti-HMGCR, Anti-TIF1, etc. Treatment for myositis depends on the underlying cause...
- Perez Y, Birk OS (February 2023). "Limb girdle muscular disease caused by HMGCR mutation and statin myopathy treatable with mevalonolactone". Proc Natl...
- anti-SRP antibody-positive immune-mediated necrotizing myopathy (30-40%), anti-HMGCR antibody-positive immune-mediated necrotizing myopathy (26-50%), and seronegative...
- acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid...
- directly inhibit the enzymatic biosynthesis of steroids. HMG-CoA reductase (HMGCR) inhibitors, also known as statins, prevent the conversion of HMG-CoATooltip...
- or normal. Electrolyte panel, anion gap, glucose, vitamin D, TSH, anti-HMGCR and AChR autoantibodies to rule-out pseudometabolic myopathies. Exercise...
- phosphorylates and inactivates 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), a key enzyme in cholesterol synthesis. HMGR converts 3-hydroxy-3-methylglutaryl-CoA...