- herpesvirus-****ociated ubiquitin-specific
protease (
HAUSP), is an
enzyme that in
humans is
encoded by the USP7 gene. USP7 or
HAUSP is a
ubiquitin specific protease or...
- that
HAUSP is
mainly localized in the nucleus,
though a
fraction of it can be
found in the
cytoplasm and mitochondria.
Overexpression of
HAUSP results...
- 2005). "ATM-mediated
phosphorylations inhibit Mdmx/Mdm2
stabilization by
HAUSP in
favor of p53 activation". Cell Cycle. 4 (9): 1166–1170. doi:10.4161/cc...
- Luo J,
Nikolaev AY, Qin J, Gu W (April 2002). "Deubiquitination of p53 by
HAUSP is an
important pathway for p53 stabilization". Nature. 416 (6881): 648–53...
-
suppressor R****F1A
promotes MDM2 self-ubiquitination by
disrupting the MDM2-DAXX-
HAUSP complex". The EMBO Journal. 27 (13): 1863–74. doi:10.1038/emboj.2008.115...
- linking/jumping
clones of
human chromosome 3:
mapping of the TFRC, RAB7 and
HAUSP genes to
regions rearranged in
leukemia and
deleted in
solid tumors". FEBS...
- (2006). "ATM-mediated
phosphorylations inhibit Mdmx/Mdm2
stabilization by
HAUSP in
favor of p53 activation". Cell Cycle. 4 (9): 1166–70. doi:10.4161/cc...
- activation,
while inhibiting regulators of the
protein such as MDM2 or
HAUSP. In
pathways that do not use p53 in
inducing apoptosis, PML have been shown...
-
Shanmugham A, Ovaa H,
Perrakis A,
Sixma TK (October 2011). "Mechanism of USP7/
HAUSP activation by its C-terminal ubiquitin-like
domain and
allosteric regulation...
-
suppressor R****F1A
promotes MDM2 self-ubiquitination by
disrupting the MDM2-DAXX-
HAUSP complex". The EMBO Journal. 27 (13): 1863–1874. doi:10.1038/emboj.2008.115...
