Definition of Gyrase. Meaning of Gyrase. Synonyms of Gyrase

- DNA gyrase, or simply gyrase, is an enzyme within the class of topoisomerase and is a subclass of Type II topoisomerases that reduces topological strain...
- Reverse gyrase is a type I topoisomerase that introduces positive supercoils into DNA, contrary to the typical negative supercoils introduced by the type...
- decreases the linking number by 2. Gyrase is also able to remove knots from the bacterial chromosome. Along with gyrase, most prokaryotes also contain a...
- was DNA gyrase from bacteria, by Martin Gellert and coworkers in 1976, and also characterized by Nicholas Cozzarelli and co-workers. DNA gyrase catalyzes...
- proteins. The obligate aerobes were later found to have a defective DNA gyrase subunit A gene (gyrA), while obligate anaerobes were defective in topoisomerase...
- secondary structures and to prevent them from re-annealing. In addition, DNA gyrase is needed to relieve the topological stress created by the action of DnaB...
- been examined. Aminocoumarins are very potent inhibitors of bacterial DNA gyrase and work by targeting the GyrB subunit of the enzyme involved in energy...
- replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase III, RNAse H, and DNA ligase...
- proteins that can bind to DNA gyrase, protecting it from the action of quinolones. Finally, mutations at key sites in DNA gyrase or topoisomerase IV can decrease...
- Glutamate racemase performs the additional function of gyrase inhibition, preventing gyrase from binding to DNA. Glutamate racemase (MurI) serves two...