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Granzyme B (GrB) is one of the
serine protease granzymes most
commonly found in the
granules of
natural killer cells (NK cells) and
cytotoxic T cells....
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Granzymes are
serine proteases released by
cytoplasmic granules within cytotoxic T
cells and
natural killer (NK) cells. They
induce programmed cell death...
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Granzyme A (GzmA, EC 3.4.21.78, CTLA3, HuTPS, T-cell ****ociated
protease 1,
cytotoxic T
lymphocyte serine protease, TSP-1, T-cell
derived serine proteinase)...
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Granzyme K (GrK) is a
protein that is
encoded by the GZMK gene on
chromosome 5 in humans.
Granzymes are a
family of
serine proteases which have various...
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Granzyme B is a
serine protease that in
humans is
encoded by the GZMB gene.
Granzyme B is
expressed by
cytotoxic T
lymphocytes (CTL) and
natural killer...
- angiogenesis,
blood coagulation,
abolishing detachment activity by GrB (
Granzyme B), and
tumour metastasis. HS has also been
shown to
serve as cellular...
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collectively termed granzymes and
include 4
distinct gene products:
granzyme A,
granzyme B,
granzyme H, and Met-ase, also
known as
granzyme M. GRCh38: Ensembl...
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protease Granzyme B,
cytotoxic T-cells and NK
cells are able to
induce apoptosis in
target cell. SCs
produce PI-9 that
irreversibly bonds Granzyme B and...
- p****ive
diffusion of a
family of pro-apoptotic proteases,
known as the
granzymes, into the
target cell. The
lytic membrane-inserting part of
perforin is...
- (subscription required)
Jonsson AH,
Zhang F,
Dunlap G, et al. (June 2022). "
Granzyme K+ CD8 T
cells form a core po****tion in
inflamed human tissue". Science...
