Definition of Granulysin. Meaning of Granulysin. Synonyms of Granulysin

- Granulysin (GNLY) is a protein expressed in most mammals which functions as an antimicrobial peptide released by killer lymphocytes in cytotoxic granules...
- release of a number of molecules, including perforin, granzyme B, and granulysin. Other agents, including tumor necrosis factor alpha and Fas ligand, also...
- somatic cells, TC cells release the cytotoxins perforin, granzymes, and granulysin. Through the action of perforin, granzymes enter the cytoplasm of the...
- allowing ions, water and toxins to enter. The entry of another toxin called granulysin (a protease) induces the target cell to undergo apoptosis. T cell killing...
- Krensky AM, Mody CH (September 2004). "NK cells use perforin rather than granulysin for anticryptococcal activity". Journal of Immunology. 173 (5): 3357–3365...
- Granule Defensins TLR4 Cathelicidin (LL37) P2X7, FPR2 Eosinophil-derived neurotoxin TLR2 Granulysin TLR4 Plasma membrane Syndecans TLR4 Glypicans TLR4...
- infected or dysfunctional somatic cells, effector CTL release perforin and granulysin: cytotoxins that form pores in the target cell's plasma membrane, allowing...
- involved in immune system defense against microbial disease (example: granulysin is protective against Mycobacterium tuberculosis ) or are targeted receptors...
- member of the SAPLIP (saposin-like protein) family along with amoebapore, granulysin, acid sphingomyelinase, surfactant protein B, and the 4 sphingolipid activator...
- Sawaya MR, Cascio D, Ernst W, Modlin R, Krensky A, Eisenberg D (2003). "Granulysin crystal structure and a structure-derived lytic mechanism". J. Mol. Biol...