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Glypicans constitute one of the two
major families of
heparan sulfate proteoglycans, with the
other major family being syndecans. Six
glypicans have been...
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subunit has a size of ~40 kDa and the C-terminal
subunit is ~30 kDa. Six
glypicans (GPC1-6) have been
identified in mammals. Cell
surface heparan sulfate...
- R,
Karihaloo A,
Tsiokas L, Chan B, et al. (April 2001). "Cell
surface glypicans are low-affinity
endostatin receptors".
Molecular Cell. 7 (4): 811–822...
- Y,
Sasisekharan R,
Cantley L,
Sukhatme VP (April 2001). "Cell
surface glypicans are low-affinity
endostatin receptors" (PDF).
Molecular Cell. 7 (4): 811–22...
- 4518. PMID 9070915. "Entrez Gene: GPC5
glypican 5". De Cat B,
David G (2001). "Developmental
roles of the
glypicans". Semin. Cell Dev. Biol. 12 (2): 117–25...
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Glypican-6 is a
protein that in
humans is
encoded by the GPC6 gene. The
glypicans comprise a
family of glycosylphosphatidylinositol-anc****d
heparan sulfate...
- PMC 5600520. PMID 28898695. Li N,
Spetz MR, Ho M (December 2020). "The Role of
Glypicans in
Cancer Progression and Therapy". The
Journal of
Histochemistry and...
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transmembrane syndecans and the
glycosylphosphatidylinositol (GPI) anc****d
glypicans.
Other minor forms of
membrane HSPG
include betaglycan and the V-3 isoform...
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expressed doubt regarding the
involvement of PTEN or GPC3,
which codes for
glypican 3 and may play a role in
regulating cell
division and
growth regulation...
- 2012). "High-affinity
monoclonal antibodies to cell
surface tumor antigen glypican-3
generated through a
combination of
peptide immunization and flow cytometry...
