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Glypicans constitute one of the two
major families of
heparan sulfate proteoglycans, with the
other major family being syndecans. Six
glypicans have been...
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Glypican-3 is a
protein that, in humans, is
encoded by the GPC3 gene. The GPC3 gene is
located on
human X
chromosome (Xq26)
where the most
common gene...
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Glypican-1 (GPC1) is a
protein that in
humans is
encoded by the GPC1 gene. GPC1 is
encoded by
human GPC1 gene
located at 2q37.3. GPC1
contains 558 amino...
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Glypican 2 (GPC2), also
known cerebroglycan, is a
protein which in
humans is
encoded by the GPC2 gene. The GPC2 gene is at
locus 7q22.1 and
encodes for...
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expressed doubt regarding the
involvement of PTEN or GPC3,
which codes for
glypican 3 and may play a role in
regulating cell
division and
growth regulation...
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Glypican-6 is a
protein that in
humans is
encoded by the GPC6 gene. The
glypicans comprise a
family of glycosylphosphatidylinositol-anc****d
heparan sulfate...
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Glypican-5 is a
protein that in
humans is
encoded by the GPC5 gene. Cell
surface heparan sulfate proteoglycans are
composed of a membrane-****ociated protein...
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Glypican-4 is a
protein that in
humans is
encoded by the GPC4 gene. Cell
surface heparan sulfate proteoglycans are
composed of a membrane-****ociated protein...
- Chen W, Man YG, Figg WD, et al. (March 2013). "Therapeutically
targeting glypican-3 via a conformation-specific single-domain
antibody in hepatocellular...
-
receptor through the
binding of
proteins such as the
stabilizers Dally and
glypican 3 (GPC3),
which inhibit diffusion. In
cancer cells, both the
heparan sulfate...
