-
Enoxolone (INN, BAN; also
known as
glycyrrhetinic acid or
glycyrrhetic acid) is a
pentacyclic triterpenoid derivative of the beta-amyrin type obtained...
- is
hydrolysed to 18β-
glycyrrhetinic acid (enoxolone) by
intestinal bacteria.
After absorption from the gut, 18β-
glycyrrhetinic acid is
metabolised to...
- w****s
appear to be
caused by
glycyrrhizic acid (75 to 540 mg per day
glycyrrhetinic acid)
causing increases in
blood pressure.
Consuming large amounts of...
- day for
several w****s,
leading to
death due to
chronic high
levels of
glycyrrhetinic acid, a prin****l
metabolite of
glycyrrhizinic acid. The resultant...
-
Farese RV Jr,
Biglieri EG,
Shackleton CHL,
Irony I, Gomez-Fontes R.
glycyrrhetinic acid-induced hypermineralocorticoidism. N Engl J Med 1991;325:1223-1227...
-
Dietary causes include overconsumption of licorice-containing products.
Glycyrrhetinic acid in
licorice inhibits the 11-β-HSD2
enzyme resulting in inappropriate...
-
Carbenoxolone (CBX) is a
glycyrrhetinic acid
derivative with a steroid-like structure,
similar to
substances found in the root of the
licorice plant. Carbenoxolone...
- 60–630 nM), with a
potency comparable to that of the 11β-HSD2
inhibitor glycyrrhetinic acid. This
action of
fluoxymesterone is
unique among AAS and is likely...
- 11β-HSD2. 11α-OHP is a more
potent inhibitor of 11β-HSD than
enoxolone (
glycyrrhetinic acid) or
carbenoxolone in
vitro (IC50 = 0.9 nM; IC50 = 5 nM in transfected...
-
Moisturiser and for
regenerating and
firming skin 1
Vitamin E
Antioxidant 1-2
Glycyrrhetinic acid For
calming skin and
minimising irritation 4
Liquid paraffin Emollient...
