- of the ribosome. However, the
glycylcyclines appear to bind more
effectively than the tetracyclines.
While glycylcyclines have
greater efficacy against...
- a new
generation of
tetracycline antibacterial agents,
known as the
glycylcyclines.
These antibiotics were the
first new
drugs of the
tetracycline class...
-
limiting tetracycline's
effectiveness in
treatment of
bacterial disease.
Glycylcyclines and
fluorocyclines are new
classes of
antibiotics derived from tetracycline...
-
foundation for the
development of Sancycline, Minocycline, and
later the
Glycylcyclines.
Tetracycline has a high
affinity for
calcium and is
incorporated into...
- late 2000s and
early 2010s:
cyclic lipopeptides (such as daptomycin),
glycylcyclines (such as tigecycline),
oxazolidinones (such as linezolid), and lipiarmycins...
-
fosfomycin are less
robust and less pathogenic. Tigecycline, a
member of the
glycylcyclines antibiotics, has
proven to be an
effective therapy against Enterobacteriaceae...
- "Pharmacokinetics and
pharmacodynamics of the
tetracyclines including glycylcyclines". The
Journal of
Antimicrobial Chemotherapy. 58 (2): 256–65. doi:10...
- the
first ketolide 2003 –
daptomycin 2005 – tigecycline, the
first glycylcycline 2005 –
doripenem 2009 – telavancin, the
first lipoglycopeptide 2010...
- Meclocycline‡
Metacycline Minocycline Omadacycline Oxytetracycline Penimepicycline Rolitetracycline Sarecycline Tetracycline#
Glycylcyclines Tigecycline...
- "Pharmacokinetics and
pharmacodynamics of the
tetracyclines including glycylcyclines".
Journal of
Antimicrobial Chemotherapy. 58 (2): 256–265. doi:10.1093/jac/dkl224...
