-
classes of
glycosylases:
monofunctional and bifunctional.
Monofunctional glycosylases have only
glycosylase activity,
whereas bifunctional glycosylases also...
-
Glycosylases (EC 3.2) are
enzymes that
hydrolyze glycosyl compounds. They are a type of
hydrolase (EC 3). In turn,
glycosylases are
divided into two groups:...
-
repair (BER) pathway. The
human gene
encodes one of
several uracil-DNA
glycosylases.
Alternative promoter usage and
splicing of this gene
leads to two different...
-
categories of
glycosylases:
monofunctional and bifunctional.
Monofunctional glycosylases have only
glycosylase activity,
whereas bifunctional glycosylases also...
- MPG gene.
Alkyladenine DNA
glycosylase is a
specific type of DNA
glycosylase. This
subfamily of
monofunctional glycosylases is
involved in the recognition...
- categories: the
uracil DNA
glycosylases (UDGs), the helix-hairpin-helix (HhH)
glycosylases, the 3-methyl-purine
glycosylase (MPG), and the endonuclease...
- 8-Oxoguanine
glycosylase, also
known as OGG1, is a DNA
glycosylase enzyme that, in humans, is
encoded by the OGG1 gene. It is
involved in base excision...
- a DNA
glycosylase recognizes a
damaged base and
cleaves the N-glycosidic bond to
release the base,
leaving an AP site. A
variety of
glycosylases that recognize...
- DNA-formamidopyrimidine
glycosylase (EC 3.2.2.23, Fapy-DNA
glycosylase,
deoxyribonucleate glycosidase, 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA
glycosylase, 2...
-
mutagenesis in yeast. This
method involves the
fusion of a 3-methyladenine DNA
glycosylase to tetR DNA-binding domain. This has been
shown to
increase mutation...
