-
Glucuronidation is
often involved in drug
metabolism of
substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids...
-
hydroxyl groups. This
linkage process is
known as
glucuronidation (or
glucuronide conjugation).
Glucuronidation occurs mainly in the liver,
although the enzymes...
- of UDP-glucuronic acid to a
small hydrophobic molecule. This is a
glucuronidation reaction.
Alternative names:
glucuronyltransferase UDP-glucuronyl transferase...
- CYP2D6 and CYP2C9 via
aromatic ring
oxidation and
glucuronidation, then
further conjugated by
glucuronidation and sulfation. The
three active metabolites exhibit...
- via a
glycosidic bond. The
glucuronides belong to the glycosides.
Glucuronidation, the
conversion of
chemical compounds to glucuronides, is a method...
-
epicatechin metabolites (SREM). The main
metabolic pathways for
SREMs are
glucuronidation,
sulfation and
methylation of the
catechol group by catechol-O-methyl...
-
glucuronosyltransferase (UDP-glucuronosyltransferase, UDPGT), an
enzyme of the
glucuronidation pathway that
transforms small lipophilic (fat-soluble) molecules, such...
-
months after birth.
Lorazepam may also
inhibit fetal liver bilirubin glucuronidation,
leading to
neonatal jaundice.
Lorazepam is
present in
breast milk...
- One of the
metabolites that may
result can be
formed through the
glucuronidation of galantamine. Additionally,
galantamine may
undergo oxidation or...
- body. The bilirubin-UGT
enzyme performs a
chemical reaction called glucuronidation.
Glucuronic acid is
transferred to
unconjugated bilirubin,
which is...
