-
Glucuronidation is
often involved in drug
metabolism of
substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids...
-
hydroxyl groups. This
linkage process is
known as
glucuronidation (or
glucuronide conjugation).
Glucuronidation occurs mainly in the liver,
although the enzymes...
- of UDP-glucuronic acid to a
small hydrophobic molecule. This is a
glucuronidation reaction.
Alternative names:
glucuronyltransferase UDP-glucuronyl transferase...
-
Biotransformation is the
biochemical modification of one
chemical compound or a
mixture of
chemical compounds.
Biotransformations can be
conducted with...
- 3-hydroxydesloratadine in a three-step
sequence in
normal metabolizers. First, N-
glucuronidation of
desloratadine by UGT2B10; then, 3-hydroxylation of desloratadine...
- CYP2D6 and CYP2C9 via
aromatic ring
oxidation and
glucuronidation, then
further conjugated by
glucuronidation and sulfation. The
three active metabolites exhibit...
- body. The bilirubin-UGT
enzyme performs a
chemical reaction called glucuronidation.
Glucuronic acid is
transferred to
unconjugated bilirubin,
which is...
-
possible therapeutic applications.
Quercetin is
rapidly metabolized (via
glucuronidation)
after the
ingestion of
quercetin foods or supplements. Five metabolites...
- via a
glycosidic bond. The
glucuronides belong to the glycosides.
Glucuronidation, the
conversion of
chemical compounds to glucuronides, is a method...
- One of the
metabolites that may
result can be
formed through the
glucuronidation of galantamine. Additionally,
galantamine may
undergo oxidation or...
