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Glucocerebroside (also
called glucosylceramide) is any of the
cerebrosides in
which the
monosaccharide head
group is glucose. In Gaucher's disease, the...
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Glucosylceramide is
found at low
levels in
animal cells such as the spleen, erythrocytes, and
nervous tissues,
especially neurons.
Glucosylceramide is...
-
disorder in
which glucocerebroside (a sphingolipid, also
known as
glucosylceramide) ac****ulates in
cells and
certain organs. The
disorder is characterized...
- deacylase, GcSM deacylase,
glucosylceramide sphingomyelin deacylase,
sphingomyelin glucosylceramide deacylase, SM
glucosylceramide GCer deacylase, SM-GCer...
- synthase, UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-
glucosylceramide acetylgalactosaminyltransferase, UDP-N-acetyl-D-galactosamine:1-O-...
-
glucosyltransferase (or
glucosylceramide synthase) is a
glucosyltransferase enzyme involved in the
production of
glucocerebrosides (also
called glucosylceramides). It is...
- form ceramide-1-phosphate. Alternatively, it may be
glycosylated by
glucosylceramide synthase or
galactosylceramide synthase. Additionally, it can be converted...
- the
tartrate salt, the
compound is
believed to work by
inhibition of
glucosylceramide synthase.
According to an
article in
Journal of the
American Medical...
- to
targeting glucosylceramide synthase.
Based on
fundamental studies by his
group and
others demonstrating a role for
glucosylceramide metabolism in...
- UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-
glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase) with
systematic name...
