-
Geranylgeranylation is a form of prenylation,
which is a post-translational
modification of
proteins that
involves the
attachment of one or two 20-carbon...
-
prenylation is CXC, which, in the Ras-related
protein Rab3A,
leads to
geranylgeranylation on both
cysteine residues and
methyl esterification. The
third motif...
- used in the post-translational
modification by the
process called geranylgeranylation.
Geranylgeraniol is a
potent inhibitor of
Mycobacterium tuberculosis...
-
WASPs and
cannot lead to
nucleation of F-actin. The GDIs' C-terminal
geranylgeranylation is
crucial for
their membrane ****ociation and function. This post-translational...
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presence of FBXL2 at
membranes via
geranylgeranylation, and is
sensitive to GGTi-2418 (a CaaX
peptidomimetic geranylgeranylation inhibitor that
reached clinical...
-
isoprenoid group (e.g.
farnesol and geranylgeraniol)
farnesylation geranylgeranylation glypiation,
glycosylphosphatidylinositol (GPI)
anchor formation via...
-
encoded by the CHML gene. The
product of the CHML gene
supports geranylgeranylation of most Rab
proteins and may
substitute for REP-1 in
tissues other...
- E, Löwik C, van der
Pluijm G,
Papapoulos S (1999). "The role of
geranylgeranylation in bone
resorption and its
suppression by
bisphosphonates in fetal...
-
Pledger WJ,
Berndt N,
Hamilton A,
Sebti SM.
Blockade of
protein geranylgeranylation inhibits Cdk2-dependent p27Kip1
Phosphorylation on Thr187 and ac****ulates...
-
Westover KD,
Deisenhofer J,
Seabra MC (Sep 1998). "Mechanism of Rab
geranylgeranylation:
formation of the
catalytic ternary complex". Biochemistry. 37 (36):...
