-
Geranylgeranyl pyrophosphate is an
intermediate in the
biosynthesis of
diterpenes and diterpenoids. It is also the
precursor to carotenoids, gibberellins...
-
Protein prenylation involves the
transfer of
either a
farnesyl or a
geranylgeranyl moiety to C-terminal cysteine(s) of the
target protein.
There are three...
- by plants,
animals and
fungi via the HMG-CoA
reductase pathway, with
geranylgeranyl pyrophosphate being a
primary intermediate.
Diterpenes form the basis...
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Acyclic Phytol Geranylgeranyl pyrophosphate Geranyl-linalool
Monocyclic Retinol Retinal Bicyclic cis-Abienol
Epimanool Salvinorin A
Tricyclic Cembrene...
-
diterpenoids with 20-carbon skeletons,
which are
biosynthesized from
geranylgeranyl pyrophosphate.
Ginkgolide B, specifically, is a
diterpenoid trilactone...
-
large diterpene class of
plant metabolites,
forskolin is
derived from
geranylgeranyl pyrophosphate (GGPP).
Forskolin contains some
unique functional elements...
- C-terminal
modification is prenylation.
During prenylation, a farnesyl- or
geranylgeranyl-isoprenoid
membrane anchor is
added to a
cysteine residue near the C-terminus...
-
formation of
geranyl pyrophosphate (GPP),
farnesyl pyrophosphate (FPP), and
geranylgeranyl pyrophosphate (GGPP). In both MVA and MEP pathways, IPP is isomerized...
-
pyrophosphate gives sesquiterpenoids, and
hydrolysis of
intermediates from
geranylgeranyl pyrophosphate gives diterpenoids, etc. In air,
terpenoids are converted...
- 7.7.67, CDP-2,3-di-O-
geranylgeranyl-sn-glycerol synthase, CTP:2,3-GG-GP
ether cytidylyltransferase, CTP:2,3-di-O-
geranylgeranyl-sn-glycero-1-phosphate...
