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Gephyrin is a
protein that in
humans is
encoded by the GPHN gene. This gene
encodes a
neuronal ****embly
protein that
anchors inhibitory neurotransmitter...
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microtubule structures.
Gephyrin also ****ists in
clustering GABA
receptors at
synapses and
molybdenum cofactor synthesis.
Because of
gephyrin's multi-functional...
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competitive antagonist of GlyR.
Cannabinoids enhance the function. The
protein Gephyrin has been
shown to be
necessary for GlyR
clustering at
inhibitory synapses...
- GABA-receptor-****ociated
protein (GABARAP).
Autoantibodies against amphiphysin and
gephyrin are also
sometimes found in SPS patients. The
antibodies appear to interact...
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localizations that are
involved in
memory formation.
Palmitoylation of
gephyrin has been
reported to
influence GABAergic synapses. DHHC
domain Myristoylation...
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Templeton and a team of
researchers looked at
mutations encomp****ing the
gephyrin gene of
chromosome 14 and were able to
trace the
split back to the last...
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Carbonetto S,
Wiseman PW, Ribeiro-da-Silva A, De
Koninck Y (June 2014). "
Gephyrin Clusters Are
Absent from
Small Diameter Primary Afferent Terminals Despite...
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identified as a
regulator of the
localization of
gephyrin,
inducing the
formation of
submembrane gephyrin aggregates that ac****ulate
glycine and GABA receptors...
-
Carbonetto S,
Wiseman PW, Ribeiro-da-Silva A, De
Koninck Y (June 2014). "
Gephyrin Clusters Are
Absent from
Small Diameter Primary Afferent Terminals Despite...
- Buchmeier, S.; Meier, J. C.; Schwarz, G. (2008). "Splice-specific
Functions of
Gephyrin in
Molybdenum Cofactor Biosynthesis".
Journal of
Biological Chemistry....