Definition of Geminin. Meaning of Geminin. Synonyms of Geminin

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Definition of Geminin

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Meaning of Geminin from wikipedia

- Geminin, DNA replication inhibitor, also known as GMNN, is a protein in humans encoded by the GMNN gene. A nuclear protein present in most eukaryotes...
- complex. In G1, levels of geminin are kept low by the APC, which ubiquitinates geminin to target it for degradation. When geminin is destro****, Cdt1 is released...
- Geminin coiled-coil domain-containing protein 1 (GEMC1) is a Geminin family chromatin-binding protein encoded by the GMNC gene located on Chromosome 3...
- the cell cycle is tightly regulated during the S phase by the protein geminin, which inhibits it, and by SCFSKP2, which ubiquinates the protein to tag...
- and RFP-geminin and identified the pulses of ERK activity with  the scoring and then align this ERK activity profiles with time of GFP-geminin induction...
- of a protein known as geminin. Geminin binds tightly to Cdt1 and is thought to be the major inhibitor of re-replication. Geminin first appears in S-phase...
- progression. Geminin is a protein that binds to Cdt1 which prevents its binding to the origin recognition complex (ORC). APCCdh1 targets geminin for ubiquitination...
- define novel regulators of early embryonic development. These included Geminin (Gmnn), a novel nuclear protein that she identified based on its ability...
- CDKs. APC, an E3 enzyme, ubiquitinates the protein geminin and targets it for degradation. Geminin normally prevents origin licensing by binding to and...
- Metazoans have a fourth mechanism to prevent re-replication; during S and G2 geminin binds to Cdt1 and inhibits Cdt1 from loading MCM2-7 onto the origin of...