Definition of Geldanamycin. Meaning of Geldanamycin. Synonyms of Geldanamycin

- Geldanamycin is a 1,4-benzoquinone ansamycin antitumor antibiotic that inhibits the function of Hsp90 (Heat Shock Protein 90) by binding to the unusual...
- a variety of cancers. Hsp90 inhibitors include the natural products geldanamycin, Retaspimycin hydrochloride (IPI 504, a hydroquinone hydrochloride salt...
- azithromycin The antihelminthics ivermectin Ansamycins The antitumor agents geldanamycin and macbecin, The antibiotic rifamycin Polyenes The antifungals amphotericin...
- chemical compound which is a semi-synthetic derivative of the antibiotic geldanamycin. It is being studied for the possibility of treating cancer. WO application...
- Another variation consists of benzene or a benzoquinone ring system as in geldanamycin or ansamitocin. Ansamycins were first discovered in 1959 by Sensi et...
- (17-N-allylamino-17-demethoxygeldanamycin, 17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specifically in younger...
- MutL) superfamily. A common binding pocket for ATP and the inhibitor geldanamycin is situated in the N-terminal domain. Amino acids that are directly involved...
- it is obtained as a byproduct, or contaminant, at the fermentation of geldanamycin. It is also called polyetherin A, azalomycin M, helixin C, antibiotic...
- fungi. These include the cephalosporin producing Acremonium chrysogenum. Geldanamycin is produced by Streptomyces hygroscopicus. Erythromycin is produced by...
- Beaulieu, Carole (4 March 2017). "Streptomyces cameroonensis sp. nov., a Geldanamycin Producer That Promotes Theobroma cacao Growth". Microbes and Environments...