Definition of Gapmers. Meaning of Gapmers. Synonyms of Gapmers

Here you will find one or more explanations in English for the word Gapmers. Also in the bottom left of the page several parts of wikipedia pages related to the word Gapmers and, of course, Gapmers synonyms and on the right images related to the word Gapmers.

Definition of Gapmers

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Meaning of Gapmers from wikipedia

- the gapmer to the target has a higher affinity due to the modified RNA flanking regions, as well as resistance to degradation by nucleases. Gapmers are...
- ossification. Antisense-mediated therapy, specifically using allele-selective LNA gapmers, has emerged as a promising strategy for FOP. This approach targets the...
- oligonucleotides (ASOs) known as gapmers can aid in decreasing the mutant RNA repeat transcripts. In the study, the gapmers tested contained specific modified...
- Pieter Cullis. In 2020, they identified antisense oligonucleotides called gapmers that knock down the expression of a toxic gene called DUX4 in cell and...
- Yokota T (2020-07-14). "Inhibition of DUX4 expression with antisense LNA gapmers as a therapy for facioscapulohumeral muscular dystrophy". Proceedings of...
- on strain-promoted alkyne-azide cycloadditions: an MXD3 mRNA targeting gapmer (cEt and PS modified) linked to an anti-CD22 antibody targeting preB cells...