-
autosomal recessive and
affect males and
females equally. GM1
gangliosidoses - GM1 GM2
gangliosidoses - GM2 Sphingolipidoses#Overview Prayson,
Richard A. (2012)...
- The GM2
gangliosidoses are a
group of
three related genetic disorders that
result from a
deficiency of the
enzyme beta-hexosaminidase. This
enzyme catalyzes...
- The GM1
gangliosidoses,
usually shortened to GM1, are
gangliosidoses caused by
mutation in the GLB1 gene
resulting in a
deficiency of beta-galactosidase...
-
disorders Gangliosidoses (including Tay–Sachs
disease (E75.0-E75.1) - they are a
subtype of
sphingolipidoses Sphingolipidoses that are not
gangliosidoses, including...
- needed] GM1
storage disease, one of a
family of
conditions called GM1
gangliosidoses, is a recessive,
genetic disorder that is
inevitably fatal. It is caused...
-
second monosialic ganglioside discovered. It is ****ociated with GM2
gangliosidoses such as Tay–Sachs disease.
Ganglioside GM2
activator protein Sphingolipidoses...
- juvenile- or adult-onset forms. Gangliosides:
Gangliosidosis GM1
gangliosidoses GM2
gangliosidoses Tay–Sachs
disease Sandhoff disease GM2-gangliosidosis, AB...
-
Mahuran DJ (1999). "Biochemical
consequences of
mutations causing the GM2
gangliosidoses".
Biochimica et
Biophysica Acta (BBA) -
Molecular Basis of Disease....
- of the
sphingolipidoses may be
classified into
either GM1
gangliosidoses or GM2
gangliosidoses. Tay–Sachs
disease belongs to the latter.[citation needed]...
-
neurodegenerative disorders are underway: Niemann-Pick
disease type C, GM2
gangliosidoses (Tay-Sachs and
Sandhoff diseases), and ataxia–telangiectasia. In 2020...
