- A
ganglioside is a
molecule composed of a
glycosphingolipid (ceramide and oligosaccharide) with one or more
sialic acids (e.g. N-acetylneuraminic acid...
- In
organic chemistry, GM2 is a type of
ganglioside. G
refers to
ganglioside, the M is for
monosialic (as in it has one
sialic acid), and 2
refers to the...
- (monosialotetrahexosylganglioside) the "prototype"
ganglioside, is a
member of the
ganglio series of
gangliosides which contain one
sialic acid residue. GM1 has...
-
Antiganglioside antibodies that
react to self-
gangliosides are
found in
autoimmune neuropathies.
These antibodies were
first found to
react with cerebellar...
- In enzymology, a
ganglioside galactosyltransferase (EC 2.4.1.62) is an
enzyme that
catalyzes the
chemical reaction UDP-galactose +...
-
activity of the enzyme,
which results in the build-up of the
molecule GM2
ganglioside within cells,
leading to toxicity.
Diagnosis may be
supported by measuring...
- the
cofactor GM2
activator protein catalyze the
degradation of the GM2
gangliosides and
other molecules containing terminal N-acetyl hexosamines. Gene mutations...
- GM3 (monosialodihexosylganglioside) is a type of
ganglioside. The
letter G
refers to
ganglioside, and M is for
monosialic acid as it has only one sialic...
-
catabolic enzymes are
needed to
degrade the
neuronal membrane components,
ganglioside GM2, its
derivative GA2, the
glycolipid globoside in
visceral tissues...
- GM2
ganglioside activator also
known as GM2A is a
protein which in
humans is
encoded by the GM2A gene. The
protein encoded by this gene is a
small glycolipid...
