-
enzymatically converts to
galactonate. Once formed,
galactonate may
enter the
pentose phosphate pathway. Thus,
oxidation to
galactonate serves as an alternate...
- The
enzyme galactonate dehydratase (EC 4.2.1.6)
catalyzes the
chemical reaction D-
galactonate ⇌ {\displaystyle \rightleftharpoons } 2-dehydro-3-deoxy-D-galactonate...
-
reaction ATP + 2-dehydro-3-deoxy-D-
galactonate ⇌ {\displaystyle \rightleftharpoons } ADP + 2-dehydro-3-deoxy-D-
galactonate 6-phosphate Thus, the two substrates...
-
aldolase (EC 4.1.2.21)
catalyzes the
chemical reaction 2-dehydro-3-deoxy-D-
galactonate 6-phosphate ⇌ {\displaystyle \rightleftharpoons }
pyruvate + D-glyceraldehyde...
- glucose-6-phosphate
dehydrogenase (NAD+) EC 1.1.1.389: 2-dehydro-3-deoxy-L-
galactonate 5-dehydrogenase EC 1.1.1.390:
sulfoquinovose 1-dehydrogenase EC 1.1.1...
-
Children with
Duarte Galactosemia:
Utility of Galactose, Galactitol,
Galactonate, and
Galactose 1-Phosphate".
Clinical Chemistry. 56 (7): 1177–1182. doi:10...
-
aconitate hydratase EC 4.2.1.5:
arabinonate dehydratase EC 4.2.1.6:
galactonate dehydratase EC 4.2.1.7:
altronate dehydratase EC 4.2.1.8:
mannonate dehydratase...
-
pathways of
glucose metabolism and
leads to
galactitol and
galactonate formation.
Galactonate is
metabolized by the
pentose phosphate pathway, and is not...
-
metabolites seen in
babies with
classic galactosemia – e.g. galactose, Gal-1P,
galactonate, and
galactitol – but to a
lesser extent.
While it
remains unclear whether...
-
cyclase * EC 5.5.1.24:
tocopherol cyclase * EC 5.5.1.25: 3,6-anhydro-L-
galactonate cycloisomerase * EC 5.5.1.26:
nogalonic acid
methyl ester cyclase * EC...
