-
GABAB receptors (GABABR) are G-protein
coupled receptors for gamma-aminobutyric acid (GABA),
therefore making them
metabotropic receptors, that are linked...
-
certain brain areas. It acts on the GHB
receptor and is a weak
agonist at the
GABAB receptor. GHB has been used in the
medical setting as a
general anesthetic...
- GABA receptors:
GABAA and
GABAB.
GABAA receptors are ligand-gated ion
channels (also
known as
ionotropic receptors);
whereas GABAB receptors are G protein-coupled...
- acid (GABA), and
hence is a GABA analogue.
Phenibut is
thought to act as a
GABAB receptor agonist,
similarly to
baclofen and γ-hydroxybutyrate (GHB). However...
- GABA receptors,
specifically the
GABAB receptors.
Baclofen produces its
effects by
selectively activating the
GABAB receptor.
Baclofen is
postulated to...
-
postsynaptic potential (IPSP) in
normal solution is −70 mV,
contrasting the
GABAB IPSP (−100 mV). The
active site of the
GABAA receptor is the
binding site...
-
compounds that
primarily act on the
GABAB receptor but also
exhibit a
range of
effects that were
found not to be
produced by
GABAB activity and so were suspected...
- 2-Hydroxysaclofen is a
GABAB receptor antagonist and an
analogue of saclofen. 2-Hydroxysaclofen
binds to the
GABAB receptor, but this is
selective for...
-
Volatile organic compounds (e.g., chloroform,
diethyl ether, sevoflurane)
GABAB receptor ligands include: 1,4-Butanediol
Baclofen GABA
Gabamide GABOB gamma-Butyrolactone...
-
mechanism of
action of
chlorzoxazone is thought[by whom?] to act on
GABAA and
GABAB receptors and voltage-gated
calcium channels to a degree.[medical citation...
