-
GABAB receptors (GABABR) are G-protein
coupled receptors for gamma-aminobutyric acid (GABA),
therefore making them
metabotropic receptors, that are linked...
- GABA receptors:
GABAA and
GABAB.
GABAA receptors are ligand-gated ion
channels (also
known as
ionotropic receptors);
whereas GABAB receptors are G protein-coupled...
-
certain brain areas. It acts on the GHB
receptor and is a weak
agonist at the
GABAB receptor. GHB has been used in the
medical setting as a
general anesthetic...
- GABA receptors,
specifically the
GABAB receptors.
Baclofen produces its
effects by
selectively activating the
GABAB receptor.
Baclofen is
postulated to...
- acid (GABA), and
hence is a GABA analogue.
Phenibut is
thought to act as a
GABAB receptor agonist,
similarly to
baclofen and γ-hydroxybutyrate (GHB). However...
-
VGCCs and, to a
lesser extent,
GABAB receptor agonist.
Baclofen (β-(4-chlorophenyl)-GABA) –
antispasmodic drug;
potent GABAB receptor agonist, weak inhibitor...
-
GABAB receptors. The G protein-coupled
receptors have
seven hydrophobic transmembrane domains. Most of them are
monomeric proteins,
although GABAB receptors...
- acid or β-(4-fluorophenyl)-GABA) is a
GABAB receptor agonist which was
never marketed. It is
selective for the
GABAB receptor over the
GABAA receptor (IC50...
- that
primarily act on the
GABAB receptor, but also
exhibit a
range of
effects which were
found not to be
produced by
GABAB activity, and so were suspected...
-
prototypical GABAB agonist), and was able to
produce analgesia via the
GABAB receptor, an
effect that was
abolished when CGP-35348, a
GABAB receptor antagonist...
