-
highly conserved P-loop "G domain", a
protein domain common to many
GTPases.
GTPases function as
molecular switches or
timers in many
fundamental cellular...
-
family of
GTPases is a
family of
small (~21 kDa)
signaling G proteins, and is a
subfamily of the Ras superfamily. The
members of the Rho
GTPase family have...
- (GDP). The best-known
members are the Ras
GTPases and
hence they are
sometimes called Ras
subfamily GTPases. A
typical G-protein is
active when bound...
-
small GTPases.
Small GTPases act as
molecular switches in
intracellular signaling pathways and have many
downstream targets. The most well-known
GTPases comprise...
- Rac is a
subfamily of the Rho
family of
GTPases,
small (~21 kDa)
signaling G
proteins (more
specifically a
GTPase). Just as
other G proteins, Rac acts as...
- is a
GTPase-activating protein. Furthermore, YopE is a
protein domain that is a Rho
GTPase-activating
protein (GAP),
which targets small GTPases such...
- is a single-subunit
small GTPase,
which is
related in
structure to the Gα
subunit of
heterotrimeric G
proteins (large
GTPases). G
proteins function as...
-
protein (more
specifically a
GTPase), and is a
member of the Rho
family of
GTPases. Chp was
identified in 1998 as a
GTPase interacting with the p21 activated...
-
signaling processes functioning as a
critical regulator in the
activity of
GTPases.
GTPases act as
molecular switches,
cycling between an
active GTP-bound state...
- Rho
GTPases. TCL is
unrelated to TCL1A, a proto-oncogene
implicated in the
development of T-Cell Leukemias. TCL1A
Ridley A. (2006). "Rho
GTPases and actin...
