Definition of GSDMD. Meaning of GSDMD. Synonyms of GSDMD

Here you will find one or more explanations in English for the word GSDMD. Also in the bottom left of the page several parts of wikipedia pages related to the word GSDMD and, of course, GSDMD synonyms and on the right images related to the word GSDMD.

Definition of GSDMD

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Meaning of GSDMD from wikipedia

- Gasdermin D (GSDMD, from combination of gastro and dermato, referencing the locations where its family of proteins were originally found to be primarily...
- cytosolic gasdermin D (GSDMD). GSDMD can be cleaved to produce an N-terminal domain (GSDMD-N) and a C-terminal domain (GSDMD-C). GSDMD-N can oligomerize and...
- non-infected patients is not uncommon. Gasdermin D (GSDMD) is a protein that in humans is encoded by the GSDMD gene and is a known target of the inflammasome...
- 18 (IL-18), as well as the pore-forming molecule gasdermin D (GSDMD). The N-terminal GSDMD fragment resulting from this cleavage induces a pro-inflammatory...
- activates complex IIb, leading to apoptosis, or pyroptosis by cleaving GSDMD. The disabling of the IKK checkpoint can also indirectly activate complex...
- HGNC:13311 Q96QA5 6680 GSDMB HGNC:23690 Q8TAX9 6681 GSDMC HGNC:7151 Q9BYG8 6682 GSDMD HGNC:25697 P57764 6683 GSDME HGNC:2810 O60443 6684 GSE1 HGNC:28979 Q14687...
- A crucial downstream substrate for pyroptotic caspases is Gasdermin D (GSDMD) Inflammation is a protective attempt by an organism to restore a homeostatic...
- Yinghua; Cai, Tao; Wang, Fengchao; Shao, Feng (2015-10-29). "Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death". Nature. 526...
- activation, the protein gasdermin D (GSDMD) forms pores in the plasma membrane. Kagan and Broz independently found that GSDMD pores serve as membrane channels...
- promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis". Cell Death Discovery. 9 (1): 26. doi:10.1038/s41420-023-01326-z...