- together,
GPCRs may
signal through G-protein-independent mechanisms, and
heterotrimeric G-proteins may play
functional roles independent of
GPCRs.
GPCRs may...
-
GPCRs – are the
simplest homomeric GPCR oligomers.
Receptor heterodimers –
which consist of two
different GPCRs – are the
simplest heteromeric GPCR oligomers...
-
receptors (
GPCRs) that span the cell membrane.
Signaling molecules bind to a
domain of the
GPCR located outside the cell, and an
intracellular GPCR domain...
- of
adhesion GPCRs that
distinguishes them from
other GPCRs is
their hybrid molecular structure. The
extracellular region of
adhesion GPCRs can be exceptionally...
- The
class C G-protein-coupled
receptors (InterPro: IPR000337) are a
class of G-protein
coupled receptors that
include the
metabotropic glutamate receptors...
- Xue C (ed.). "The
origin of
GPCRs:
identification of
mammalian like Rhodopsin, Adhesion,
Glutamate and
Frizzled GPCRs in fungi". PLOS ONE. 7 (1): e29817...
-
induce their responses on G protein-coupled
receptors (
GPCRs). Many
types of
Inverse agonists for
GPCRs have been
shown to
exhibit the
following conventionally...
-
known superfamily members include the rhodopsin-like
GPCRs (this family), the secretin-like
GPCRs, the cAMP receptors, the
fungal mating pheromone receptors...
- two-step
mechanism for
regulating the
activity of G protein-coupled
receptors (
GPCRs) in the
visual rhodopsin system by
Hermann Kühn,
Scott Hall, and Ursula...
-
response to
activation of cell
surface G protein-coupled
receptors (
GPCRs).
GPCRs function as part of a three-component
system of receptor-transducer-effector...
