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Gelsolin is an actin-binding
protein that is a key
regulator of
actin filament ****embly and dis****embly.
Gelsolin is one of the most
potent members of...
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Familial Amyloidosis,
Finnish Type (FAF), also
called hereditary gelsolin amyloidosis and AGel
amyloidosis (AGel), is an
amyloid condition with a number...
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Plasma gelsolin (pGSN) is an 83 kDa
abundant protein constituent of
normal plasma and an
important component of the
innate immune system. The identification...
- hematologist, inventor,
medical researcher, and writer, who
discovered gelsolin and
invented the
BioAegis technology estate. He was also a
professor emeritus...
- ****ociated with
manifestations of
systemic amyloidosis due to ac****ulation of
gelsolin. ****ociated
conditions may
include cutis laxa and ataxia. type III is also...
- "Localization of the calcium-sensitive
actin monomer binding site in
gelsolin to
segment 4 and
identification of
calcium binding sites". Biochemistry...
-
transthyretin (ATTR, the most
commonly implicated protein),
apolipoprotein A1, and
gelsolin. Due to the
rareness of the
other types of
familial neuropathies, transthyretin...
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humans is
encoded by the FLII gene. This gene
encodes a
protein with a
gelsolin-like
actin binding domain and an N-terminal leucine-rich repeat-protein...
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mutations in ITM2B.
Familial amyloidosis-Finnish type is ****ociated with
gelsolin amyloid (AGel). CAA is ****ociated with
brain hemorrhages, particularly...
-
humans is
encoded by the CAPG gene. This gene
encodes a
member of the
gelsolin/villin
family of actin-regulatory proteins. The
encoded protein reversibly...
