Definition of GARFT. Meaning of GARFT. Synonyms of GARFT

Here you will find one or more explanations in English for the word GARFT. Also in the bottom left of the page several parts of wikipedia pages related to the word GARFT and, of course, GARFT synonyms and on the right images related to the word GARFT.

Definition of GARFT

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Meaning of GARFT from wikipedia

- dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). By inhibiting the formation of precursor purine and pyrimidine nucleotides...
- specifically targeting the enzyme glycinamide ribonucleotide formyltransferase (GARFT). It has been studied for its potential in inhibiting tumor growth by reducing...
- more of three enzymes that use folate and derivatives as substrates: DHFR, GARFT and thymidylate synthase. Raltitrexed is fully active after polyglutamylation...
- infections and GI effects. Pemetrexed Antineoplastic Mammalian DHFR, TS, GARFT +++ D Non-small cell lung carcinoma & mesothelioma Nausea, vomiting, dyspnoea...