-
GABAB receptors (GABABR) are G-protein
coupled receptors for gamma-aminobutyric acid (GABA),
therefore making them
metabotropic receptors, that are linked...
- GABA receptors:
GABAA and
GABAB.
GABAA receptors are ligand-gated ion
channels (also
known as
ionotropic receptors);
whereas GABAB receptors are G protein-coupled...
- GABA receptors,
specifically the
GABAB receptors.
Baclofen produces its
effects by
selectively activating the
GABAB receptor.
Baclofen is
postulated to...
-
certain brain areas. It acts on the GHB
receptor and is a weak
agonist at the
GABAB receptor. GHB has been used in the
medical setting as a
general anesthetic...
- acid (GABA), and
hence is a GABA analogue.
Phenibut is
thought to act as a
GABAB receptor agonist,
similarly to
baclofen and γ-hydroxybutyrate (GHB). However...
-
VGCCs and, to a
lesser extent,
GABAB receptor agonist.
Baclofen (β-(4-chlorophenyl)-GABA) –
antispasmodic drug;
potent GABAB receptor agonist, weak inhibitor...
- acid or β-(4-fluorophenyl)-GABA) is a
GABAB receptor agonist which was
never marketed. It is
selective for the
GABAB receptor over the
GABAA receptor (IC50...
-
postsynaptic potential (IPSP) in
normal solution is −70 mV,
contrasting the
GABAB IPSP (−100 mV). The
active site of the
GABAA receptor is the
binding site...
-
Volatile organic compounds (e.g., chloroform,
diethyl ether, sevoflurane)
GABAB receptor ligands include: 1,4-Butanediol
Baclofen GABA
Gabamide GABOB gamma-Butyrolactone...
- that
primarily act on the
GABAB receptor, but also
exhibit a
range of
effects which were
found not to be
produced by
GABAB activity, and so were suspected...
