-
class I,
whereas Fumarase C is a part of the
class II
fumarases.
Figure 1
depicts the
fumarase reaction mechanism. Two
residues catalyze proton transfer...
-
Fumarase deficiency (or
fumaric aciduria) is an
exceedingly rare
autosomal recessive metabolic disorder in the
Krebs cycle,
characterized by a deficiency...
-
Similarities and
Differences between the
Catalytic [4Fe-4S]
Cluster Containing Fumarases FumA and FumB from
Escherichia coli", PLOS ONE, 8 (2) (published 6 February...
- {\displaystyle K_{\mathrm {m} }} .
Diffusion limited enzymes, such as
fumarase, work at the
theoretical upper limit of 108 – 1010 M−1s−1,
limited by diffusion...
- triose-phosphate isomerase,
carbonic anhydrase, acetylcholinesterase, catalase,
fumarase, β-lactamase, and
superoxide di****ase.: 8.4.2 The
turnover of such enzymes...
-
where they
generate the
equivalent of 1.5 ATP 8
Hydration Fumarate + H2O
Fumarase L-Malate
Hydration of C-C
double bond 9
Oxidation L-Malate + NAD+ Malate...
- of the
Short Cr****
Community are
reported to have a high
incidence of
fumarase deficiency, an
extremely rare
genetic disease. It
causes encephalopathy...
- death. The
Colorado City/Hildale area has the world's
highest incidence of
fumarase deficiency, an
extremely rare
genetic disease.
Geneticists attribute this...
- coli fumC) as well as in eukaryotes. The
sequence of the two
classes of
fumarases are not
closely related. Adenylosuccinase, EC 4.3.2.2 (adenylosuccinate...
- The
fumarate released in the
cytosol is
hydrated to
malate by
cytosolic fumarase. This
malate is then
oxidized to
oxaloacetate by
cytosolic malate dehydrogenase...
