- Li–
Fraumeni syndrome (LFS) is a rare,
autosomal dominant,
hereditary disorder that
predisposes carriers to
cancer development. It was
named after two American...
-
Fraumeni is an
Italian surname.
Notable people with the
surname include:
Barbara Fraumeni (born 1949),
American economist Joseph F.
Fraumeni Jr. (born...
-
Joseph F.
Fraumeni Jr. (born
April 1, 1933) is an
American physician and
cancer researcher. Born in Boston, he
received an A.B. from
Harvard College, an...
-
Barbara Morry Fraumeni (born
December 9, 1949) is a Special-term
Professor at the
Central University of
Finance and Economics, a
Senior Fellow at Hunan...
- most
famous for his discovery,
together with his
colleague Joseph Fraumeni, of Li–
Fraumeni syndrome,
which is
caused by
germline mutations of the p53 tumor...
- risk
factors include genetic disorders, such as
neurofibromatosis and Li–
Fraumeni syndrome, and
previous radiation therapy.
Glioblastomas represent 15% of...
-
syndrome of
esophageal cancer with tylosis,
juvenile polyposis syndrome, Li–
Fraumeni syndrome,
multiple endocrine neoplasia type 1/2,
multiple osteochondromatosis...
- Beckwith–Wiedemann syndrome,
trisomy 18,
trisomy 21,
Acardi syndrome, Li–
Fraumeni syndrome,
Goldenhar syndrome, von
Gierke disease, and
familial adenomatous...
- 342–51. doi:10.1038/onc.2011.241. PMID 21685942.
Malkin D (April 2011). "Li-
fraumeni syndrome".
Genes Cancer. 2 (4): 475–84. doi:10.1177/1947601911413466. PMC 3135649...
- risk of bone sarcoma.
Certain inherited genetic syndromes,
including Li-
Fraumeni syndrome,
inherited RB1 gene mutations, and Paget's
disease of bone are...
