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Formimidoyltransferase cyclodeaminase or
formiminotransferase cyclodeaminase (gene
symbol FTCD in humans) is a
bifunctional enzyme that
catalyzes the following...
-
formimidoyltetrahydrofolate cyclodeaminase activity. The
formiminotransferase (FT)
domain of
formiminotransferase-cyclodeaminase (FTCD)
forms a homodimer, with each...
- also be
produced as an
intermediate in
histidine catabolism, by
formiminotransferase cyclodeaminase, from 5-formiminotetrahydrofolate. 5,10-CH=THF is...
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Vrielink A (2000). "The
crystal structure of the
formiminotransferase domain of
formiminotransferase-cyclodeaminase:
implications for
substrate channeling...
-
methylmalonic acid,
increased folate and a
decrease in homocysteine.
Formiminotransferase cyclodeaminase Glutamate-1-semialdehyde
Glutamic acid Imidazol-4-one-5-propionic...
-
common use
include formiminoglycine formiminotransferase, FIG
formiminotransferase, and
glycine formiminotransferase. This
enzyme parti****tes in purine...
-
glutamate formiminotransferase domain (which
catalyses the
previous step in the pathway) to form the
bifunctional enzyme formiminotransferase cyclodeaminase...
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formimidoyltransferase and then
converted into 5,10-methenyltetrahydrofolate by
formiminotransferase cyclodeaminase.
Fowler B (February 2001). "The
folate cycle and disease...
- EC 2.1.2.4:
glycine formimidoyltransferase EC 2.1.2.5:
glutamate formiminotransferase EC 2.1.2.6: deleted,
included in EC 2.1.2.5 EC 2.1.2.7: D-alanine...
- Physician.; in this context, "Arakawa
syndrome 1"
refers to
Glutamate formiminotransferase deficiency.
Online Mendelian Inheritance in Man (OMIM): 156570 synd/235...
