-
Floxuridine (also 5-
fluorodeoxyuridine) is an
oncology drug that
belongs to the
class known as antimetabolites. Specifically,
floxuridine is a pyrimidine...
- 5'-monophosphate, is a
molecule formed in vivo from 5-fluorouracil and 5-
fluorodeoxyuridine.
FdUMP acts as a
suicide inhibitor of
thymidylate synthase (TS). By...
- Right: 5-Fluorodeoxyuridylate monophosphate, a
metabolite formed from 5-fluorouracil and 5-
fluorodeoxyuridine,
which includes a
fluoropyrimidine moiety....
- D, camptothecin, methotrexate,
methyl acrylate,
resorcinol and 5-
fluorodeoxyuridine. Additionally, 1,2-dimethylhydrazine is a
known colon carcinogen and...
- edu.
Retrieved 2021-06-29. Ingraham,
Holly Ann (1981).
Effects of 5-
fluorodeoxyuridine on
intracellular metabolism of
deoxyuridylate (Thesis). OCLC 13198098...
- from the parent.
While the
phenomenon was
mentioned as a
result of
fluorodeoxyuridine treatment as
early as 1979 and egg-laying
mutants were identified...
- used
inhibitor is 5-fluorouracil (5-FU) and its
metabolized form 5-
fluorodeoxyuridine monophosphate (5-FdUMP),
which acts as an
antimetabolite that irreversibly...
- CH2-THF = 5,10-methylenetetrahydrofolate, DHF = dihydrofolate,
FdUMP =
fluorodeoxyuridine-5′-monophosphate, dUMP =
deoxyuridine monophosphate, dTMP = deoxythymidine...
-
prospective randomized trial of
regional versus systemic continuous 5-
fluorodeoxyuridine chemotherapy in the
treatment of
colorectal liver metastases". Annals...
