-
Fludarabine is a
purine analogue and
antineoplastic agent. It is
generally used as its 5-O-phosphorylated form
known as
fludarabine phosphate, sold under...
-
survival than
single agents: FC (
fludarabine with cyclophosphamide) FR (
fludarabine with rituximab) FCR (
fludarabine, cyclophosphamide, and rituximab)...
-
Capecitabine Cladribine Clofarabine Cytarabine Decitabine Doxifluridine Fludarabine Fluorouracil Gemcitabine Hydroxyurea Mercaptopurine Methotrexate Nelarabine...
- The
acronym incorporates the
three primary ingredients of the regimen:
Fludarabine: an
antimetabolite that,
while not
active toward AML,
increases formation...
-
Hensel M,
Steinbrecher C, et al. (February 2006). "
Fludarabine plus
cyclophosphamide versus fludarabine alone in first-line
therapy of
younger patients with...
- are used
primarily to
treat hairy cell leukemia.
Nucleotide analogues Fludarabine inhibits multiple DNA polymerases, DNA primase, and DNA
ligase I, and...
-
because of this
treatment and is
therefore not used on a
regular basis.
Fludarabine is a drug
normally used to
treat hematological malignancies and acts...
-
healthy blood cells. It is used
together with
another medicine called fludarabine in
adults and
children from one
month of age with
blood cancers as well...
-
chemotherapeutic agents that have
induced neurotoxicity include 5-fluorouracil and
fludarabine.
Besides its role in chemotherapy,
methotrexate is also used as an orally...
- not to be
active in t(11;18) disease. The
purine nucleoside analogs fludarabine and
cladribine also
demonstrate activity, the
latter conferring a CR...
