-
Protoporphyrin ferrochelatase (EC 4.98.1.1,
formerly EC 4.99.1.1, or
ferrochelatase;
systematic name
protoheme ferro-lyase (protoporphyrin-forming)) is...
- and can be very painful. It
arises from a
deficiency in the
enzyme ferrochelatase,
leading to
abnormally high
levels of
protoporphyrin in the red blood...
- The
enzyme sirohydrochlorin ferrochelatase (EC 4.99.1.4)
catalyzes the
following reaction:
siroheme + 2H+ ⇌ {\displaystyle \rightleftharpoons } sirohydrochlorin...
-
cyclase and
guanylyl cyclase EC 4.99
includes other lyases, such as
ferrochelatase Some
lyases ****ociate with
biological membranes as
peripheral membrane...
- growth. In the
human body, lead
inhibits porphobilinogen synthase and
ferrochelatase,
preventing both
porphobilinogen formation and the
incorporation of...
- This
protoporphyrin molecule chelates with iron in
presence of
enzyme ferrochelatase to
produce Heme. Heme
increases the
mitochondrial activity thereby helping...
- porphyrins.
Erythropoietic protoporphyria (EPP) is
caused by a
deficiency in
ferrochelatase,
leading to the ac****ulation of
protoporphyrin IX in red
blood cells...
- 1016/S0959-440X(00)00124-X. ISSN 0959-440X. PMID 11042447. "Pfam entry:
Ferrochelatase".
Archived from the
original on 2007-09-29.
Retrieved 2007-01-25. Al-Karadaghi...
- not
ligands per se, but the
conjugate acids thereof. In the case of
ferrochelatases, the
reaction that
chelatases catalyze is: Fe2+ + H2P → FeP + 2 H+...
- hemoglobin. Lead also
inhibits the
enzyme ferrochelatase,
another enzyme involved in the
formation of heme.
Ferrochelatase catalyzes the
joining of protoporphyrin...
