Definition of Farnesyltransferase. Meaning of Farnesyltransferase. Synonyms of Farnesyltransferase

Here you will find one or more explanations in English for the word Farnesyltransferase. Also in the bottom left of the page several parts of wikipedia pages related to the word Farnesyltransferase and, of course, Farnesyltransferase synonyms and on the right images related to the word Farnesyltransferase.

Definition of Farnesyltransferase

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Meaning of Farnesyltransferase from wikipedia

- Farnesyltransferase (EC 2.5.1.58) is one of the three enzymes in the prenyltransferase group. Farnesyltransferase (FTase) adds a 15-carbon isoprenoid...
- methylation. Carboxyl methylation only occurs on prenylated proteins. Farnesyltransferase and geranylgeranyltransferase I are very similar proteins. They consist...
- The farnesyltransferase inhibitors (FTIs) are a class of experimental cancer drugs that target protein farnesyltransferase with the downstream effect of...
- name Zarnestra) is a farnesyltransferase inhibitor. Farnesyltransferase inhibitors block the activity of the farnesyltransferase enzyme by inhibiting...
- triggers three sequential enzymatic modifications. First, protein farnesyltransferase catalyzes the addition of a farnesyl moiety to the cysteine. Second...
- Farnesyl-diphosphate farnesyltransferase 1 is a protein that in humans is encoded by the FDFT1 gene. This gene encodes a membrane-****ociated enzyme located...
- 1126/science.1153018. PMC 2747771. PMID 18276850. Farnesyl-Diphosphate+Farnesyltransferase at the U.S. National Library of Medicine Medical Subject Headings...
- systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming). This enzyme catalyses the following...
- affinity modulator Sickle cell disease 2019 Lonafarnib (Zokinvy) Farnesyltransferase inhibitor Hutchinson-Gilford progeria syndrome 2020 2022 Dupilumab...
- onto the C-terminal consensus sequence CAAL (somewhat similar to farnesyltransferase reactions), where C=cysteine, A=any aliphatic amino acid, and L=leucine...