Definition of Farnesoid. Meaning of Farnesoid. Synonyms of Farnesoid

- The bile acid receptor (BAR), also known as farnesoid X receptor (FXR) or NR1H4 (nuclear receptor subfamily 1, group H, member 4), is a nuclear receptor...
- also have hormonal actions throughout the body, particularly through the farnesoid X receptor and GPBAR1 (also known as TGR5). Bile acid synthesis is the...
- was identified in 1999 as the most active physiological ligand for the farnesoid X receptor (FXR), which is involved in many physiological and pathological...
- in placebo-controlled, randomized clinical trials to be effective. The farnesoid X receptor agonist obeticholic acid has shown clinical and biochemical...
- the farnesoid X receptor is partly responsible for lipid and glucose homeostasis, as well as pathogen recognition. An agonist for the farnesoid X receptor...
- safety. In 2013, ivermectin was demonstrated as a novel ligand of the farnesoid X receptor, a therapeutic target for nonalcoholic fatty liver disease...
- does not. Cafestol may act as an agonist ligand for the nuclear receptor farnesoid X receptor and pregnane X receptor, blocking cholesterol homeostasis....
- E-guggulsterone and Z-guggulsterone. In humans, it acts as an antagonist of the farnesoid X receptor, which was once believed to result in decreased cholesterol...
- Omesdafexor (MET409) is a small-molecule farnesoid X receptor (FXR) agonist developed for nonalcoholic steatohepatitis and colitis. https://www.journal-of-hepatology...
- significant discoveries are the constitutive androstane receptor (CAR) in 1994, farnesoid X receptor (FXR) in 1995, and the small heterodimer partner (SHP) in 1996...